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LATS2 Pre-design Chimera RNAi

  • Catalog # : H00026524-R03
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens LATS, large tumor suppressor, homolog 2 (Drosophila) (LATS2), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_014572
  • Target Region:
  • Coding sequence
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Gene Name:
  • LATS2
  • Gene Alias:
  • FLJ13161,KPM
  • Gene Description:
  • LATS, large tumor suppressor, homolog 2 (Drosophila)
  • Gene Summary:
  • This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq
  • Other Designations:
  • LATS (large tumor suppressor, Drosophila) homolog 2,LATS, large tumor suppressor, homolog 2,OTTHUMP00000018106,kinase phosphorylated during mitosis protein,serine/threonine kinase KPM,warts-like kinase
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