PTPN18 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
PTPN18 transfected lysate.
Western Blot
Lane 1: PTPN18 transfected lysate ( 38.72 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-PTPN18 full-length
Host
Human
Theoretical MW (kDa)
38.72
Interspecies Antigen Sequence
Mouse (74); Rat (73)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-PTPN18 antibody (H00026469-B01) by Western Blots.
SDS-PAGE Gel
PTPN18 transfected lysate.
Western Blot
Lane 1: PTPN18 transfected lysate ( 38.72 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — PTPN18
Entrez GeneID
26469GeneBank Accession#
BC052800.1Protein Accession#
AAH52800.1Gene Name
PTPN18
Gene Alias
BDP1, PTP-HSCF
Gene Description
protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
Omim ID
606587Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
brain-derived phosphatase|protein tyrosine phosphatase, non-receptor type 18
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