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PTPN18 mouse monoclonal antibody (hybridoma)

  • Catalog # : H00026469-M
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against a full-length recombinant PTPN18.
  • Immunogen:
  • PTPN18 (AAH52800.1, 1 a.a. ~ 351 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
  • Sequence:
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactivity and specificity confirmed by ELISA and Western Blot.
  • Note:
  • Customer should check the viability of the hybridomas within one month from the date of receipt. Fee-for-service of long term hybridoma storage can be performed upon customer's request.
  • Deliverables:
  • Up to 5 positive hybridoma clones will be delivered to customer in the cryotube format.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Recombinant protein)
  • Gene Information
  • Gene Name:
  • PTPN18
  • Gene Alias:
  • Gene Description:
  • protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
  • Gene Summary:
  • The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • brain-derived phosphatase,protein tyrosine phosphatase, non-receptor type 18
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