HSPB8 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
HSPB8 transfected lysate.
Western Blot
Lane 1: HSPB8 transfected lysate ( 21.60 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-HSPB8 full-length
Host
Human
Theoretical MW (kDa)
21.6
Interspecies Antigen Sequence
Mouse (94); Rat (95)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-HSPB8 antibody (H00026353-B01P) by Western Blots.
SDS-PAGE Gel
HSPB8 transfected lysate.
Western Blot
Lane 1: HSPB8 transfected lysate ( 21.60 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — HSPB8
Entrez GeneID
26353GeneBank Accession#
NM_014365.2Protein Accession#
NP_055180.1Gene Name
HSPB8
Gene Alias
CMT2L, DHMN2, E2IG1, H11, HMN2, HMN2A, HSP22
Gene Description
heat shock 22kDa protein 8
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq
Other Designations
E2-induced gene 1|heat shock 27kDa protein 8|heat shock protein beta-8|protein kinase H11|small stress protein-like protein HSP22
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Interactome
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Disease
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