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Last updated: 2016/10/16
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HSPB8 Validated Chimera RNAi

  • Catalog # : H00026353-R01V
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  • Specification
  • Product Description:
  • Homo sapiens heat shock 22kDa protein 8 (HSPB8), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_014365
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown (Antibody validated)
  • RNAi Knockdown (Antibody validated)
  • Western blot analysis of HSPB8 over-expressed 293 cell line, cotransfected with HSPB8 Validated Chimera RNAi ( Cat # H00026353-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with HSPB8 monoclonal antibody (M01) clone 2E11-1F3 (Cat # H00026353-M01 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.
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  • Application Image
  • RNAi Knockdown (Antibody validated)
  • RNAi Knockdown (Antibody validated)
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  • Gene Information
  • Gene Name:
  • HSPB8
  • Gene Alias:
  • Gene Description:
  • heat shock 22kDa protein 8
  • Gene Summary:
  • The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq
  • Other Designations:
  • E2-induced gene 1,heat shock 27kDa protein 8,heat shock protein beta-8,protein kinase H11,small stress protein-like protein HSP22
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