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HSPB8 monoclonal antibody (M04A), clone 5B12

  • Catalog # : H00026353-M04A
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against a partial recombinant HSPB8.
  • Immunogen:
  • HSPB8 (NP_055180, 97 a.a. ~ 196 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
  • Sequence:
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Isotype:
  • IgG2a Kappa
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.

    QC Testing of H00026353-M04A
    Western Blot detection against Immunogen (36.74 KDa) .
  • Storage Buffer:
  • In ascites fluid
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of HSPB8 expression in transfected 293T cell line by HSPB8 monoclonal antibody (M04A), clone 5B12.

    Lane 1: HSPB8 transfected lysate(35.446 KDa).
    Lane 2: Non-transfected lysate.
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Western Blot (Recombinant protein)
  • Gene Information
  • Gene Name:
  • HSPB8
  • Gene Alias:
  • Gene Description:
  • heat shock 22kDa protein 8
  • Gene Summary:
  • The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq
  • Other Designations:
  • E2-induced gene 1,heat shock 27kDa protein 8,heat shock protein beta-8,protein kinase H11,small stress protein-like protein HSP22
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