HSPB8 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
HSPB8 MaxPab polyclonal antibody. Western Blot analysis of HSPB8 expression in human colon.
Western Blot (Transfected lysate)
Western Blot analysis of HSPB8 expression in transfected 293T cell line (H00026353-T02) by HSPB8 MaxPab polyclonal antibody.
Lane 1: HSPB8 transfected lysate(21.56 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human HSPB8 protein.
Immunogen
HSPB8 (NP_055180.1, 1 a.a. ~ 196 a.a) full-length human protein.
Sequence
MADGQMPFSCHYPSRLRRDPFRDSPLSSRLLDDGFGMDPFPDDLTASWPDWALPRLSSAWPGTLRSGMVPRGPTATARFGVPAEGRTPPPFPGEPWKVCVNVHSFKPEELMVKTKDGYVEVSGKHEEKQQEGGIVSKNFTKKIQLPAEVDPVTVFASLSPEGLLIIEAPQVPPYSTFGESSFNNELPQDSQEVTCT
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (94); Rat (95)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
HSPB8 MaxPab polyclonal antibody. Western Blot analysis of HSPB8 expression in human colon.Western Blot (Transfected lysate)
Western Blot analysis of HSPB8 expression in transfected 293T cell line (H00026353-T02) by HSPB8 MaxPab polyclonal antibody.
Lane 1: HSPB8 transfected lysate(21.56 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — HSPB8
Entrez GeneID
26353GeneBank Accession#
NM_014365.2Protein Accession#
NP_055180.1Gene Name
HSPB8
Gene Alias
CMT2L, DHMN2, E2IG1, H11, HMN2, HMN2A, HSP22
Gene Description
heat shock 22kDa protein 8
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq
Other Designations
E2-induced gene 1|heat shock 27kDa protein 8|heat shock protein beta-8|protein kinase H11|small stress protein-like protein HSP22
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Interactome
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Disease
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