VPS33B monoclonal antibody (M01), clone 3E11
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant VPS33B.
Immunogen
VPS33B (NP_061138.2, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MAFPHRPDAPELPDFSMLKRLARDQLIYLLEQLPGKKDLFIEADLMSPLDRIANVSILKQHEVDKLYKVENKPALSSNEQLCFLVRPRIKNMRYIASLVN
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
VPS33B monoclonal antibody (M01), clone 3E11. Western Blot analysis of VPS33B expression in K-562.Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged VPS33B is 3 ng/ml as a capture antibody.ELISA
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Gene Info — VPS33B
Entrez GeneID
26276GeneBank Accession#
NM_018668.3Protein Accession#
NP_061138.2Gene Name
VPS33B
Gene Alias
FLJ14848
Gene Description
vacuolar protein sorting 33 homolog B (yeast)
Gene Ontology
HyperlinkGene Summary
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and encodes the human ortholog of rat Vps33b which is homologous to the yeast class C Vps33 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. [provided by RefSeq
Other Designations
vacuolar protein sorting 33B|vacuolar protein sorting 33B (yeast homolog))
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Interactome
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Disease
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