SENP3 (Human) Recombinant Protein (P01)
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Specification
Product Description
Human SENP3 full-length ORF (1 a.a. - 191 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MSRNSLSIPVESLGHVYLMLMGSPFLGVGLTLVDSASVYPSCGLICMHESTVCIPLCFPQASLSCPFHFPCPIGLLSCTLPNGFGGQSGPEGERSLAPPDASILISNVCSIGDHVAQELFQGSDLGMAEEAERPGEKAGQHSPLREEHVTCVQSILDEFLQTYGSLIPLSTDEVVEKLEDIFQQEFSTPSR
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
46.9
Interspecies Antigen Sequence
Mouse (94); Rat (94)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SENP3
Entrez GeneID
26168GeneBank Accession#
AK000923.1Gene Name
SENP3
Gene Alias
DKFZp586K0919, DKFZp762A152, SMT3IP1, SSP3
Gene Description
SUMO1/sentrin/SMT3 specific peptidase 3
Gene Ontology
HyperlinkGene Summary
The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP3, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM
Other Designations
SUMO1/sentrin/SMT3 specific protease 3|sentrin/SUMO-specific protease 3
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Interactome
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Disease
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