APPL1 (Human) IP-WB Antibody Pair
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More Files
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Immunoprecipitation of APPL1 transfected lysate using rabbit polyclonal anti-APPL1 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse polyclonal anti-APPL1.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (93)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of APPL1 transfected lysate using rabbit polyclonal anti-APPL1 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse polyclonal anti-APPL1.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-APPL1 (300 ul)
2. Antibody pair for WB: mouse polyclonal anti-APPL1 (50 ul)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — APPL1
Entrez GeneID
26060Gene Name
APPL1
Gene Alias
APPL, DIP13alpha
Gene Description
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
Omim ID
604299Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq
Other Designations
AKT2 interactor|adaptor protein containing pH domain, PTB domain and leucine zipper motif 1|signaling adaptor protein DIP13alpha
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Interactome
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Pathway
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Disease
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