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Last updated: 2016/10/23
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APPL1 MaxPab rabbit polyclonal antibody (D01)MaxPab

  • Catalog # : H00026060-D01
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against a full-length human APPL1 protein.
  • Immunogen:
  • APPL1 (NP_036228.1, 1 a.a. ~ 709 a.a) full-length human protein.
  • Sequence:
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • No additive
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of APPL1 expression in transfected 293T cell line (H00026060-T02) by APPL1 MaxPab polyclonal antibody.

    Lane 1: APPL1 transfected lysate(79.7 KDa).
    Lane 2: Non-transfected lysate.
  • PDF DownloadProtocol Download
  • Immunoprecipitation
  • Immunoprecipitation
  • Immunoprecipitation of APPL1 transfected lysate using anti-APPL1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with APPL MaxPab mouse polyclonal antibody (B01) (H00026060-B01).
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Gene Name:
  • APPL1
  • Gene Alias:
  • APPL,DIP13alpha
  • Gene Description:
  • adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
  • Gene Summary:
  • The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq
  • Other Designations:
  • AKT2 interactor,adaptor protein containing pH domain, PTB domain and leucine zipper motif 1,signaling adaptor protein DIP13alpha
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