THEA monoclonal antibody (M01), clone 4D1
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant THEA.
Immunogen
THEA (AAH01517, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MADGEGYRNPTEVQMSQLVLPCHTNQRGELSVGQLLKWIDTTACLSAERHAGCPCVTASMDDIYFEHTISVGQVVNIKAKVNRAFNSSMEVGIQVASEDLCSEKQWNVCK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (88); Rat (88)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.73 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ACOT11 is approximately 0.03ng/ml as a capture antibody.ELISA
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Gene Info — ACOT11
Entrez GeneID
26027GeneBank Accession#
BC001517Protein Accession#
AAH01517Gene Name
ACOT11
Gene Alias
BFIT, BFIT1, BFIT2, KIAA0707, STARD14, THEA, THEM1
Gene Description
acyl-CoA thioesterase 11
Omim ID
606803Gene Ontology
HyperlinkGene Summary
This gene encodes a protein with acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. Expression of a similar murine protein in brown adipose tissue is induced by cold exposure and repressed by warmth. Expression of the mouse protein has been associated with obesity, with higher expression found in obesity-resistant mice compared with obesity-prone mice. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000011526|OTTHUMP00000011527|OTTHUMP00000046722|START domain containing 14|StAR-related lipid transfer (START) domain containing 14|brown fat inducible thioesterase|thioesterase superfamily member 1|thioesterase, adipose associated
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Interactome
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Disease
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