ACOT11 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human ACOT11 peptide using ARM Technology.
Immunogen
A synthetic peptide of human ACOT11 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human ACOT11 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — ACOT11
Entrez GeneID
26027GeneBank Accession#
ACOT11Gene Name
ACOT11
Gene Alias
BFIT, BFIT1, BFIT2, KIAA0707, STARD14, THEA, THEM1
Gene Description
acyl-CoA thioesterase 11
Omim ID
606803Gene Ontology
HyperlinkGene Summary
This gene encodes a protein with acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. Expression of a similar murine protein in brown adipose tissue is induced by cold exposure and repressed by warmth. Expression of the mouse protein has been associated with obesity, with higher expression found in obesity-resistant mice compared with obesity-prone mice. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000011526|OTTHUMP00000011527|OTTHUMP00000046722|START domain containing 14|StAR-related lipid transfer (START) domain containing 14|brown fat inducible thioesterase|thioesterase superfamily member 1|thioesterase, adipose associated
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Interactome
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Disease
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