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UPF2 Pre-design Chimera RNAi

  • Catalog # : H00026019-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens UPF2 regulator of nonsense transcripts homolog (yeast) (UPF2), transcript variant 2, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_015542
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.
    The related RNAi products listed below were designed from different accesion number but sharing the same RNAi sequence.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Gene Name:
  • UPF2
  • Gene Alias:
  • DKFZp434D222,HUPF2,KIAA1408,MGC138834,MGC138835,RENT2,smg-3
  • Gene Description:
  • UPF2 regulator of nonsense transcripts homolog (yeast)
  • Gene Summary:
  • This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene; both variants encode the same protein. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000019091,OTTHUMP00000019092,OTTHUMP00000045025,UPF2 regulator of nonsense transcripts homolog,regulator of nonsense transcripts 2,yeast Upf2p homolog
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