IBTK 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
IBTK transfected lysate.
Western Blot
Lane 1: IBTK transfected lysate ( 150.5 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-IBTK full-length
Host
Human
Theoretical MW (kDa)
150.5
Interspecies Antigen Sequence
Mouse (85)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-IBTK antibody (H00025998-B01) by Western Blots.
SDS-PAGE Gel
IBTK transfected lysate.
Western Blot
Lane 1: IBTK transfected lysate ( 150.5 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — IBTK
Entrez GeneID
25998GeneBank Accession#
NM_015525Protein Accession#
NP_056340Gene Name
IBTK
Gene Alias
BTKI, KIAA1417, MGC142256, MGC142258, RP1-93K22.1
Gene Description
inhibitor of Bruton agammaglobulinemia tyrosine kinase
Omim ID
606457Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene binds to Bruton's tyrosine kinase (BTK) and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. [provided by RefSeq
Other Designations
BTK-binding protein|Bruton agammaglobulinemia tyrosine kinase inhibitor|OTTHUMP00000040002|inhibitor of Bruton's tyrosine kinase|inhibitor of Bruton's tyrosine kinase-alpha|inhibitor of Bruton's tyrosine kinase-beta|inhibitor of Bruton's tyrosine kinase-g
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