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IBTK rabbit monoclonal antibody

  • Catalog # : H00025998-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human IBTK peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human IBTK is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human IBTK peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • GeneBank Accession#:
  • IBTK
  • Gene Name:
  • IBTK
  • Gene Alias:
  • BTKI,KIAA1417,MGC142256,MGC142258,RP1-93K22.1
  • Gene Description:
  • inhibitor of Bruton agammaglobulinemia tyrosine kinase
  • Gene Summary:
  • The protein encoded by this gene binds to Bruton's tyrosine kinase (BTK) and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. [provided by RefSeq
  • Other Designations:
  • BTK-binding protein,Bruton agammaglobulinemia tyrosine kinase inhibitor,OTTHUMP00000040002,inhibitor of Bruton's tyrosine kinase,inhibitor of Bruton's tyrosine kinase-alpha,inhibitor of Bruton's tyrosine kinase-beta,inhibitor of Bruton's tyrosine kinase-g
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