Rabbit monoclonal antibody raised against a human IBTK peptide using ARM Technology.
A synthetic peptide of human IBTK is used for rabbit immunization. Customer or Abnova will decide on the preferred peptide sequence.
Quality Control Testing:
Antibody reactive against human IBTK peptide by ELISA and mammalian transfected lysate by Western Blot.
In 1x PBS, pH 7.4
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
1. Customer may provide cell or tissue lysate for antibody screening. 2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
The protein encoded by this gene binds to Bruton's tyrosine kinase (BTK) and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. [provided by RefSeq
BTK-binding protein,Bruton agammaglobulinemia tyrosine kinase inhibitor,OTTHUMP00000040002,inhibitor of Bruton's tyrosine kinase,inhibitor of Bruton's tyrosine kinase-alpha,inhibitor of Bruton's tyrosine kinase-beta,inhibitor of Bruton's tyrosine kinase-g