SH2B (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human SH2B partial ORF ( AAH10704, 327 a.a. - 426 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
GKAKHLRLSLNEEGQCRVQHLWFQSIFDMLEHFRVHPIPLESGGSSDVVLVSYVPSSQRQQGREQAGSHAGVCEGDGCHPDASCTLMPFGASDCVTDHLP
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.63
Interspecies Antigen Sequence
Mouse (88); Rat (93)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SH2B1
Entrez GeneID
25970GeneBank Accession#
BC010704Protein Accession#
AAH10704Gene Name
SH2B1
Gene Alias
DKFZp547G1110, FLJ30542, KIAA1299, SH2-B, SH2B
Gene Description
SH2B adaptor protein 1
Omim ID
608937Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the SH2-domain containing mediators family. The encoded protein mediates activation of various kinases and may function in cytokine and growth factor receptor signaling and cellular transformation. Alternatively spliced transcript variants have been described. [provided by RefSeq
Other Designations
SH2 domain-containing putative adapter SH2-B|SH2-B alpha signaling protein|SH2-B gamma signaling protein|SH2-B homolog
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Interactome
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Pathway
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Disease
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