SH2B1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human SH2B1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human SH2B1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human SH2B1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — SH2B1
Entrez GeneID
25970GeneBank Accession#
SH2B1Gene Name
SH2B1
Gene Alias
DKFZp547G1110, FLJ30542, KIAA1299, SH2-B, SH2B
Gene Description
SH2B adaptor protein 1
Omim ID
608937Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the SH2-domain containing mediators family. The encoded protein mediates activation of various kinases and may function in cytokine and growth factor receptor signaling and cellular transformation. Alternatively spliced transcript variants have been described. [provided by RefSeq
Other Designations
SH2 domain-containing putative adapter SH2-B|SH2-B alpha signaling protein|SH2-B gamma signaling protein|SH2-B homolog
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