SH2B purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human SH2B protein.
Immunogen
SH2B (AAH10704.1, 1 a.a. ~ 426 a.a) full-length human protein.
Sequence
MVQREELLSFMGAEEAAPDPAGVGRGGGVAGPPSGGGGQPQWQKCRLLLRSEGEGGGGSRLEFFVPPKASRPRLSIPCSSITDVRTTTALEMPDRENTFVVKVEGPSEYIMETVDAQHVKAWVSDIQECLSPGPCPATSPRPMTLPLAPGTSFLTRENTDSLELSCLNHSESLPSQDLLLGPSESNDRLSQGAYGGLSDRPSASISPSSASIAASHFDSMELLPPELPPRIPIEEGPPAGTVHPLSAPYPPLDTPETATGSFLFQGEPEGGEGDQPLSGYPWFHGMLSRLKAAQLALTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNEEGQCRVQHLWFQSIFDMLEHFRVHPIPLESGGSSDVVLVSYVPSSQRQQGREQAGSHAGVCEGDGCHPDASCTLMPFGASDCVTDHLP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (88); Rat (93)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
SH2B MaxPab polyclonal antibody. Western Blot analysis of SH2B expression in human kidney.Western Blot (Transfected lysate)
Western Blot analysis of SH2B1 expression in transfected 293T cell line (H00025970-T01) by SH2B1 MaxPab polyclonal antibody.
Lane 1: SH2B transfected lysate(46.86 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to SH2B on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — SH2B1
Entrez GeneID
25970GeneBank Accession#
BC010704Protein Accession#
AAH10704.1Gene Name
SH2B1
Gene Alias
DKFZp547G1110, FLJ30542, KIAA1299, SH2-B, SH2B
Gene Description
SH2B adaptor protein 1
Omim ID
608937Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the SH2-domain containing mediators family. The encoded protein mediates activation of various kinases and may function in cytokine and growth factor receptor signaling and cellular transformation. Alternatively spliced transcript variants have been described. [provided by RefSeq
Other Designations
SH2 domain-containing putative adapter SH2-B|SH2-B alpha signaling protein|SH2-B gamma signaling protein|SH2-B homolog
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Interactome
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Pathway
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Disease
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