C1orf48 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human C1orf48 full-length ORF ( AAH07067.1, 1 a.a. - 281 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MAGFPELVVLDPPWDKELAAGTESQALVSATPREDFRVRCTSKRAVTEMLQLCGRFVQKLGDALPEEIREPALRDAQWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQFDEIIVDIATKRKQYPRKILECVIKTIKAKQEILKQYHPVVHPLDLKYDPDPAPHMENLKCRGETVAKEISEAMKSLPALIEQGEGFSQVLRMQPVIHLQRIHQEVFSSCHRKPDAKPENFITQIETTPTETASRKTSDVVLKRKQTKDCPQRKWYPLRPKKINLDT
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
58.6
Interspecies Antigen Sequence
Mouse (67)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — NSL1
Entrez GeneID
25936GeneBank Accession#
BC007067.1Protein Accession#
AAH07067.1Gene Name
NSL1
Gene Alias
C1orf48, DC8, DKFZp566O1646, MIS14
Gene Description
NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)
Omim ID
609174Gene Ontology
HyperlinkGene Summary
This gene encodes a protein with two coiled-coil domains that localizes to kinetochores, which are chromosome-associated structures that attach to microtubules and mediate chromosome movements during cell division. The encoded protein is part of a conserved protein complex that includes two chromodomain-containing proteins and a component of the outer plate of the kinetochore. This protein complex is proposed to bridge centromeric heterochromatin with the outer kinetochore structure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
NSL1, MIND kinetochore complex component|OTTHUMP00000034928
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Interactome
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Disease
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