NSL1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human NSL1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human NSL1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human NSL1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — NSL1
Entrez GeneID
25936GeneBank Accession#
NSL1Gene Name
NSL1
Gene Alias
C1orf48, DC8, DKFZp566O1646, MIS14
Gene Description
NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)
Omim ID
609174Gene Ontology
HyperlinkGene Summary
This gene encodes a protein with two coiled-coil domains that localizes to kinetochores, which are chromosome-associated structures that attach to microtubules and mediate chromosome movements during cell division. The encoded protein is part of a conserved protein complex that includes two chromodomain-containing proteins and a component of the outer plate of the kinetochore. This protein complex is proposed to bridge centromeric heterochromatin with the outer kinetochore structure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
NSL1, MIND kinetochore complex component|OTTHUMP00000034928
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Interactome
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