SOSTDC1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human SOSTDC1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human SOSTDC1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human SOSTDC1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — SOSTDC1
Entrez GeneID
25928GeneBank Accession#
SOSTDC1Gene Name
SOSTDC1
Gene Alias
CDA019, DKFZp564D206, ECTODIN, USAG1
Gene Description
sclerostin domain containing 1
Omim ID
609675Gene Ontology
HyperlinkGene Summary
This gene is a member of the sclerostin family and encodes an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain. This protein functions as a bone morphogenetic protein (BMP) antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death. [provided by RefSeq
Other Designations
cystine-knot containing secreted protein|ectodermal BMP inhibitor|uterine sensitization-associated protein-1
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Interactome
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