COBRA1 purified MaxPab mouse polyclonal antibody (B01P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human COBRA1 protein.
Immunogen
COBRA1 (AAH11892.1, 1 a.a. ~ 475 a.a) full-length human protein.
Sequence
MPSLQPVVMCVMKHLPKVPEKKLKLVMADKELYRACAVEVKRQIWQDNQALFGDEVSPLLKQYILEKESALFSTELSVLHNFFSPSPKTRRQGEVVQRLTRMVGKNVKLYDMVLQFLRTLFLRTRNVHYCTLRAELLMSLHDLDVGEICTVDPCHKFTWCLDACIRERFVDSKRARELQGFLDGVKKGQEQVLGDLSMILCDPFAINTLALSTVRHLQELVGQETLPRDSPDLLLLLRLLALGQGAWDMIDSQVFKEPKMEVELITRFLPMLMSFLVDDYTFNVDQKLPAEEKAPVSYPNTLPESFTKFLQEQRMACEVGLYYVLHITKQRNKNALLRLLPGLVETFGDLAFGDIFLHLLTGNLALLADEFALEDFCSSLFDGFFLTASPRKENVHRHALRLLIHLHPRVAPSKLEALQKALEPTGQSGEAVKELYSQLGEKLEQLDHRKPSPAQAAETPALELPLPSVPAPAPL
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
COBRA1 MaxPab polyclonal antibody. Western Blot analysis of COBRA1 expression in human pancreas.Western Blot (Transfected lysate)
Western Blot analysis of COBRA1 expression in transfected 293T cell line (H00025920-T01) by COBRA1 MaxPab polyclonal antibody.
Lane 1: COBRA1 transfected lysate(52.25 KDa).
Lane 2: Non-transfected lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of purified MaxPab antibody to COBRA1 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml]Immunofluorescence
Immunofluorescence of purified MaxPab antibody to COBRA1 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — COBRA1
Entrez GeneID
25920GeneBank Accession#
BC011892.1Protein Accession#
AAH11892.1Gene Name
COBRA1
Gene Alias
DKFZp586B0519, KIAA1182, NELF-B, NELFB
Gene Description
cofactor of BRCA1
Gene Ontology
HyperlinkGene Summary
NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2; MIM 606026), either NELFC or NELFD (TH1L; MIM 605297), and NELFE (RDBP; MIM 154040). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1; MIM 603555) and SPT5 (SUPT5H; MIM 602102), to cause transcriptional pausing of RNA polymerase II (see MIM 180660) (Narita et al., 2003 [PubMed 12612062]).[supplied by OMIM
Other Designations
negative elongation factor protein B
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Interactome
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