POT1 polyclonal antibody (A01)
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More Files
- More Functions
Western Blot (Cell lysate)
POT1 polyclonal antibody (A01), Lot # 060524JCS1 Western Blot analysis of POT1 expression in MES-SA/Dx5 ( Cat # L021V1 ).
Western Blot detection against Immunogen (36.56 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant POT1.
Immunogen
POT1 (NP_056265, 1 a.a. ~ 95 a.a) partial recombinant protein with GST tag.
Sequence
MSLVPATNYIYTPLNQLKGGTIVNVYGVVKFFKPPYLSKGTDYCSVVTIVDQTNVKLTCLLFSGNYEALPIIYKNGDIVRFHRLKIQVYKKETQG
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (75); Rat (75)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.56 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
POT1 polyclonal antibody (A01), Lot # 060524JCS1 Western Blot analysis of POT1 expression in MES-SA/Dx5 ( Cat # L021V1 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — POT1
Entrez GeneID
25913GeneBank Accession#
NM_015450Protein Accession#
NP_056265Gene Name
POT1
Gene Alias
DKFZp586D211, hPot1
Gene Description
POT1 protection of telomeres 1 homolog (S. pombe)
Omim ID
606478Gene Ontology
HyperlinkGene Summary
This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq
Other Designations
POT1-like telomere end-binding protein|protection of telomeres 1
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Interactome
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Disease
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