MTHFD1L rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human MTHFD1L peptide using ARM Technology.
Immunogen
A synthetic peptide of human MTHFD1L is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human MTHFD1L peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — MTHFD1L
Entrez GeneID
25902GeneBank Accession#
MTHFD1LGene Name
MTHFD1L
Gene Alias
DKFZp586G1517, FLJ21145, FTHFSDC1, MTC1THFS, dJ292B18.2
Gene Description
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
Omim ID
611427Gene Ontology
HyperlinkGene Summary
One-carbon substituted forms of tetrahydrofolate (THF) are involved in the de novo synthesis of purines and thymidylate and support cellular methylation reactions through the regeneration of methionine from homocysteine. MTHFD1L is an enzyme involved in THF synthesis in mitochondria (Christensen et al., 2005 [PubMed 15611115]).[supplied by OMIM
Other Designations
OTTHUMP00000017418|formyltetrahydrofolate synthetase domain containing 1|mitochondrial C1-tetrahydrofolate synthase|mitochondrial C1-tetrahydrofolate synthetase
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