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MTHFD1L rabbit monoclonal antibody

  • Catalog # : H00025902-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human MTHFD1L peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human MTHFD1L is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human MTHFD1L peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Gene Name:
  • MTHFD1L
  • Gene Alias:
  • DKFZp586G1517,FLJ21145,FTHFSDC1,MTC1THFS,dJ292B18.2
  • Gene Description:
  • methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
  • Gene Summary:
  • One-carbon substituted forms of tetrahydrofolate (THF) are involved in the de novo synthesis of purines and thymidylate and support cellular methylation reactions through the regeneration of methionine from homocysteine. MTHFD1L is an enzyme involved in THF synthesis in mitochondria (Christensen et al., 2005 [PubMed 15611115]).[supplied by OMIM
  • Other Designations:
  • OTTHUMP00000017418,formyltetrahydrofolate synthetase domain containing 1,mitochondrial C1-tetrahydrofolate synthase,mitochondrial C1-tetrahydrofolate synthetase
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