RCHY1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human RCHY1 full-length ORF ( NP_001009922.1, 1 a.a. - 252 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MAATAREDGASGQERGQRGCEHYDRGCLLKAPCCDKLYTCRLCHDNNEDHQLDRFKVKEVQCINCEKIQHAQQTCEECSTLFGEYYCDICHLFDKDKKQYHCENCGICRIGPKEDFFHCLKCNLCLAMNLQGRHKCIENVSRQNCPICLEDIHTSRVVAHVLPCGHLLHRGYRCPLCMHSALDMTRYWRQLDDEVAQTPMPSEYQNMTVDILCNDCNGRSTVQFHILGMKCKICESYNTAQAGGRRISLDQQ
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
55.4
Interspecies Antigen Sequence
Mouse (86); Rat (86)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — RCHY1
Entrez GeneID
25898GeneBank Accession#
NM_001009922.1Protein Accession#
NP_001009922.1Gene Name
RCHY1
Gene Alias
ARNIP, CHIMP, DKFZp586C1620, PIRH2, PRO1996, RNF199, ZNF363, hARNIP
Gene Description
ring finger and CHY zinc finger domain containing 1
Omim ID
607680Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene has ubiquitin-protein ligase activity. This protein binds with p53 and promotes the ubiquitin-mediated proteosomal degradation of p53. This gene is oncogenic because loss of p53 function contributes directly to malignant tumor development. Transcription of this gene is regulated by p53. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
CH-rich interacting match with PLAG1|androgen-receptor N-terminal-interacting protein|zinc finger protein 363
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Interactome
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Pathway
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