PRKD2 monoclonal antibody (M01), clone 2E4
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PRKD2.
Immunogen
PRKD2 (AAH25307, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MDESEDSGVIPGSHSENALHASEEEEGEGGKAQSSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDTLRKRHYWRLDCKCITLFQNNTTNRYYKEIPLSEILTVE
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (95); Rat (94)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.73 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
PRKD2 monoclonal antibody (M01), clone 2E4 Western Blot analysis of PRKD2 expression in HeLa ( Cat # L013V1 ).Western Blot (Recombinant protein)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to PRKD2 on formalin-fixed paraffin-embedded human tonsil. [antibody concentration 1 ug/ml]Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PRKD2 is approximately 1ng/ml as a capture antibody.ELISA
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Gene Info — PRKD2
Entrez GeneID
25865GeneBank Accession#
BC025307Protein Accession#
AAH25307Gene Name
PRKD2
Gene Alias
HSPC187, PKD2
Gene Description
protein kinase D2
Omim ID
607074Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
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Interactome
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Disease
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