BRMS1 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-BRMS1 full-length
Host
Human
Theoretical MW (kDa)
27.17
Interspecies Antigen Sequence
Mouse (92)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-BRMS1 antibody (H00025855-B01) by Western Blots.
SDS-PAGE Gel
BRMS1 transfected lysate.
Western Blot
Lane 1: BRMS1 transfected lysate ( 28.5 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — BRMS1
Entrez GeneID
25855GeneBank Accession#
NM_015399Protein Accession#
NP_056214Gene Name
BRMS1
Gene Alias
DKFZp564A063
Gene Description
breast cancer metastasis suppressor 1
Omim ID
606259Gene Ontology
HyperlinkGene Summary
This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
breast cancer metastasis-suppressor 1
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