BRMS1 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human BRMS1 protein.
Immunogen
BRMS1 (NP_056214.1, 1 a.a. ~ 246 a.a) full-length human protein.
Sequence
MPVQPPSKDTEEMEAEGDSAAEMNGEEEESEEERSGSQTESEEESSEMDDEDYERRRSECVSEMLDLEKQFSELKEKLFRERLSQLRLRLEEVGAERAPEYTEPLGGLQRSLKIRIQVAGIYKGFCLDVIRNKYECELQGAKQHLESEKLLLYDTLQGELQERIQRLEEDRQSLDLSSEWWDDKLHARGSSRSWDSLPPSKRKKAPLVSGPYIVYMLQEIDILEDWTAIKKARAAVSPQKRKSDGP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (92)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of BRMS1 expression in transfected 293T cell line (H00025855-T01) by BRMS1 MaxPab polyclonal antibody.
Lane 1: BRMS1 transfected lysate(27.06 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — BRMS1
Entrez GeneID
25855GeneBank Accession#
NM_015399.3Protein Accession#
NP_056214.1Gene Name
BRMS1
Gene Alias
DKFZp564A063
Gene Description
breast cancer metastasis suppressor 1
Omim ID
606259Gene Ontology
HyperlinkGene Summary
This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
breast cancer metastasis-suppressor 1
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