BAMBI rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human BAMBI peptide using ARM Technology.
Immunogen
A synthetic peptide of human BAMBI is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human BAMBI peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — BAMBI
Entrez GeneID
25805GeneBank Accession#
BAMBIGene Name
BAMBI
Gene Alias
NMA
Gene Description
BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)
Omim ID
604444Gene Ontology
HyperlinkGene Summary
This gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis. [provided by RefSeq
Other Designations
BMP and activin membrane-bound inhibitor|OTTHUMP00000019384|non-metastatic gene A protein|putative transmembrane protein
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Interactome
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Disease
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