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Last updated: 2016/11/27

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GCA Pre-design Chimera RNAi

  • Catalog # : H00025801-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens grancalcin, EF-hand calcium binding protein (GCA), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_012198
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Gene Name:
  • GCA
  • Gene Alias:
  • GCL
  • Gene Description:
  • grancalcin, EF-hand calcium binding protein
  • Gene Summary:
  • This gene product, grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation. [provided by RefSeq
  • Other Designations:
  • grancalcin, EF-hand calcium-binding protein,grancalcin, penta-EF-hand protein
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