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RASGRP3 (Human) IP-WB Antibody Pair

  • Catalog # : H00025780-PW1
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  • Specification
  • Product Description:
  • This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Immunoprecipitation-Western Blot (IP-WB)

    QC Testing of H00025780-PW1
    Immunoprecipitation of RASGRP3 transfected lysate using rabbit polyclonal anti-RASGRP3 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-RASGRP3.
  • Supplied Product:
  • Antibody pair set content:
    1. Antibody pair for IP: rabbit polyclonal anti-RASGRP3 (300 ul)
    2. Antibody pair for WB: mouse purified polyclonal anti-RASGRP3 (50 ug)
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Applications
  • Application Image
  • Immunoprecipitation-Western Blot
  • Gene Information
  • Gene Name:
  • RASGRP3
  • Gene Alias:
  • GRP3,KIAA0846
  • Gene Description:
  • RAS guanyl releasing protein 3 (calcium and DAG-regulated)
  • Gene Summary:
  • Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM
  • Other Designations:
  • guanine nucleotide exchange factor for Rap1
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