PANX1 monoclonal antibody (M07), clone 2E3
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PANX1.
Immunogen
PANX1 (NP_056183.2, 327 a.a. ~ 425 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
DLSLYNLFLEENISEVKSYKCLKVLENIKSSGQGIDPMLLLTNLGMIKMDVVDGKTPMSAEMREEQGNQTAELQGMNIDSETKANNGEKNARQRLLDSS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (86); Rat (88)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PANX1 is 1 ng/ml as a capture antibody.ELISA
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Gene Info — PANX1
Entrez GeneID
24145GeneBank Accession#
NM_015368Protein Accession#
NP_056183.2Gene Name
PANX1
Gene Alias
MGC21309, MRS1, PX1, UNQ2529
Gene Description
pannexin 1
Omim ID
608420Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties. [provided by RefSeq
Other Designations
innexin
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Interactome
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Disease
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