MAFF monoclonal antibody (M02), clone 1F8
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Specifications
Product Description
Mouse monoclonal antibody raised against a partial recombinant MAFF.
Immunogen
MAFF (NP_036455.1, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MSVDPLSSKALKIKRELSENTPHLSDEALMGLSVRELNRHLRGLSAEEVTRLKQRRRTLKNRGYAASCRVKRVCQKEELQKQKSELEREVDKLARENAAMRLELDALRGK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (89); Rat (90)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
MAFF monoclonal antibody (M02), clone 1F8. Western Blot analysis of MAFF expression in Hela S3 NE.Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged MAFF is 0.03 ng/ml as a capture antibody.ELISA
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Gene Info — MAFF
Entrez GeneID
23764GeneBank Accession#
NM_012323Protein Accession#
NP_036455.1Gene Name
MAFF
Gene Alias
U-MAF
Gene Description
v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
Omim ID
604877Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000028701|transcription factor MAFF|v-maf avian musculoaponeurotic fibrosarcoma oncogene family protein F
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