AIPL1 (Human) IP-WB Antibody Pair
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More Files
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Immunoprecipitation of AIPL1 transfected lysate using mouse monoclonal anti-AIPL1 and Protein A Magnetic Bead (U0007), and immunoblotted with rabbit polyclonal anti-AIPL1.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (87); Rat (87)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of AIPL1 transfected lysate using mouse monoclonal anti-AIPL1 and Protein A Magnetic Bead (U0007), and immunoblotted with rabbit polyclonal anti-AIPL1.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: mouse monoclonal anti-AIPL1 (300 ug)
2. Antibody pair for WB: rabbit polyclonal anti-AIPL1 (50 ul)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — AIPL1
Entrez GeneID
23746Gene Name
AIPL1
Gene Alias
AIPL2, LCA4
Gene Description
aryl hydrocarbon receptor interacting protein-like 1
Gene Ontology
HyperlinkGene Summary
Leber congenital amaurosis (LCA) accounts for at least 5% of all inherited retinal disease and is the most severe inherited retinopathy with the earliest age of onset. Individuals affected with LCA are diagnosed at birth or in the first few months of life with severely impaired vision or blindness, nystagmus and an abnormal or flat electroretinogram. The photoreceptor/pineal -expressed gene, AIPL1, encoding aryl-hydrocarbon interacting protein-like 1, was mapped within the LCA4 candidate region. The protein contains three tetratricopeptide motifs, consistent with nuclear transport or chaperone activity. AIPL1 mutations may cause approximately 20% of recessive LCA. [provided by RefSeq
Other Designations
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Interactome
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Disease
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