BHMT2 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-BHMT2 full-length
Host
Human
Theoretical MW (kDa)
40.4
Interspecies Antigen Sequence
Mouse (85); Rat (85)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-BHMT2 antibody (H00023743-D01P) by Western Blots.
SDS-PAGE Gel
BHMT2 transfected lysate.
Western Blot
Lane 1: BHMT2 transfected lysate ( 40.40 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — BHMT2
Entrez GeneID
23743GeneBank Accession#
NM_017614.3Protein Accession#
NP_060084.2Gene Name
BHMT2
Gene Alias
FLJ20001
Gene Description
betaine-homocysteine methyltransferase 2
Omim ID
605932Gene Ontology
HyperlinkGene Summary
Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. [provided by RefSeq
Other Designations
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Interactome
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Disease
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