SHPK MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human SHPK protein.
Immunogen
SHPK (NP_037408.2, 1 a.a. ~ 478 a.a) full-length human protein.
Sequence
MAARPITLGIDLGTTSVKAALLRAAPDDPSGFAVLASCARAARAEAAVESAVAGPQGREQDVSRILQALHECLAALPRPQLRSVVGIGVSGQMHGVVFWKTGQGCEWTEGGITPVFEPRAVSHLVTWQDGRCSSEFLASLPQPKSHLSVATGFGCATIFWLLKYRPEFLKSYDAAGTIHDYVVAMLCGLPRPLMSDQNAASWGYFNTQSQSWNVETLRSSGFPVHLLPDIAEPGSVAGRTSHMWFEIPKGTQVGVALGDLQASVYSCMAQRTDAVLNISTSVQLAASMPSGFQPAQTPDPTAPVAYFPYFNRTYLGVAASLNGGNVLATFVHMLVQWMADLGLEVEESTVYSRMIQAAVQQRDTHLTITPTVLGERHLPDQLASVTRISSSDLSLGHVTRALCRGIVQNLHSMLPIQQLQEWGVERVMGSGSALSRNDVLKQEVQRAFPLPMSFGQDVDAAVGAALVMLRRHLNQKES
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (87); Rat (86)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of SHPK expression in transfected 293T cell line (H00023729-T01) by SHPK MaxPab polyclonal antibody.
Lane 1: SHPK transfected lysate(51.5 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of SHPK transfected lysate using anti-SHPK MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with SHPK purified MaxPab mouse polyclonal antibody (B01P) (H00023729-B01P). -
Gene Info — SHPK
Entrez GeneID
23729GeneBank Accession#
NM_013276.2Protein Accession#
NP_037408.2Gene Name
SHPK
Gene Alias
CARKL, FLJ32478, SHK
Gene Description
sedoheptulokinase
Omim ID
605060Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements. [provided by RefSeq
Other Designations
carbohydrate kinase-like
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Interactome
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Pathway
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Disease
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