SH3BP4 monoclonal antibody (M01), clone 3F3
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SH3BP4.
Immunogen
SH3BP4 (AAH57396, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MAAQRIRAANSNGLPRCKSEGTLIDLSEGFSETSFNDIKVPSPSALLVDNPTPFGNAKEVIAIKDYCPTNFTTLKFSKGDHLYVLDTSGGEWWYAHNTTEMGYIPSSYVQ
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (96); Rat (97)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.51 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SH3BP4 is approximately 0.03ng/ml as a capture antibody.ELISA
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Gene Info — SH3BP4
Entrez GeneID
23677GeneBank Accession#
BC057396Protein Accession#
AAH57396Gene Name
SH3BP4
Gene Alias
BOG25, TTP
Gene Description
SH3-domain binding protein 4
Omim ID
605611Gene Ontology
HyperlinkGene Summary
This gene encodes a protein with 3 Asn-Pro-Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. This protein is involved in cargo-specific control of clathrin-mediated endocytosis, specifically controlling the internalization of a specific protein receptor. [provided by RefSeq
Other Designations
EH-binding protein|OTTHUMP00000164396|transferrin receptor trafficking protein
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Interactome
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Disease
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