PLA2G15 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PLA2G15 peptide using ARM Technology.
Immunogen
A synthetic peptide of human PLA2G15 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PLA2G15 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PLA2G15
Entrez GeneID
23659GeneBank Accession#
PLA2G15Gene Name
PLA2G15
Gene Alias
ACS, DKFZp564A0122, GXVPLA2, LLPL, LPLA2, LYPLA3
Gene Description
phospholipase A2, group XV
Omim ID
609362Gene Ontology
HyperlinkGene Summary
Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene hydrolyzes lysophosphatidylcholine to glycerophosphorylcholine and a free fatty acid. This enzyme is present in the plasma and thought to be associated with high-density lipoprotein. A later paper contradicts the function of this gene. It demonstrates that this gene encodes a lysosomal enzyme instead of a lysophospholipase and has both calcium-independent phospholipase A2 and transacylase activities. [provided by RefSeq
Other Designations
1-O-acylceramide synthase|LCAT-like lysophospholipase|lysophospholipase 3 (lysosomal phospholipase A2)|lysosomal phospholipase A2
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