PPP1R15A rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PPP1R15A peptide using ARM Technology.
Immunogen
A synthetic peptide of human PPP1R15A is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PPP1R15A peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PPP1R15A
Entrez GeneID
23645GeneBank Accession#
PPP1R15AGene Name
PPP1R15A
Gene Alias
GADD34
Gene Description
protein phosphatase 1, regulatory (inhibitor) subunit 15A
Omim ID
611048Gene Ontology
HyperlinkGene Summary
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation. [provided by RefSeq
Other Designations
growth arrest and DNA-damage-inducible 34|protein phosphatase 1, regulatory subunit 15A
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Interactome
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Disease
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