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KPNA6 Pre-design Chimera RNAi

  • Catalog # : H00023633-R01
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  • Specification
  • Product Description:
  • Homo sapiens karyopherin alpha 6 (importin alpha 7) (KPNA6), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_012316
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Gene Name:
  • KPNA6
  • Gene Alias:
  • FLJ11249,IPOA7,KPNA7,MGC17918
  • Gene Description:
  • karyopherin alpha 6 (importin alpha 7)
  • Gene Summary:
  • Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000004532,importin alpha 7 subunit,importin-alpha-S2,karyopherin alpha 6
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