KCNE1L (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human KCNE1L full-length ORF (BAG37431.1, 1 a.a. - 142 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MNCSESQRLRTLLSRLLLELHHRGNASGLGAGPRPSMGMGVVPDPFVGREVTSAKGDDAYLYILLIMIFYACLAGGLILAYTRSRKLVEAKDEPSQACAEHEWAPGGALTADAEAAAGSQAEGRRQLASEGLPALAQGAERV
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
42.02
Interspecies Antigen Sequence
Mouse (80); Rat (79)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — KCNE1L
Entrez GeneID
23630GeneBank Accession#
AK314923.1Protein Accession#
BAG37431.1Gene Name
KCNE1L
Gene Alias
KCNE5
Gene Description
KCNE1-like
Omim ID
300328Gene Ontology
HyperlinkGene Summary
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a membrane protein which has sequence similarity to the KCNE1 gene product, a member of the potassium channel, voltage-gated, isk-related subfamily. This intronless gene is deleted in AMME contiguous gene syndrome and may be involved in the cardiac and neurologic abnormalities found in the AMME contiguous gene syndrome. [provided by RefSeq
Other Designations
AMMECR2 protein|OTTHUMP00000023845|cardiac voltage-gated potassium channel accessory subunit 5|potassium voltage-gated channel subfamily E member 1-like protein|potassium voltage-gated channel, Isk-related family, member 1-like|voltage-gated potassium cha
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Interactome
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Disease
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