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Last updated: 2017/2/26

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SPO11 rabbit monoclonal antibody

  • Catalog # : H00023626-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human SPO11 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human SPO11 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human SPO11 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • GeneBank Accession#:
  • SPO11
  • Gene Name:
  • SPO11
  • Gene Alias:
  • MGC39953
  • Gene Description:
  • SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
  • Gene Summary:
  • Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. The protein encoded by this gene is similar in sequence and conserved features to the yeast meiotic recombination protein. The encoded protein belongs to the TOP6A protein family. Several transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been described. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000031360,OTTHUMP00000031361,SPO11 meiotic protein covalently bound to DSB-like,SPO11, meiotic protein covalently bound to DSB-like,meiotic recombination protein SPO11
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