CBLC monoclonal antibody (M01), clone 3F10
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of CBLC expression in transfected 293T cell line by CBLC monoclonal antibody (M01), clone 3F10.
Lane 1: CBLC transfected lysate (Predicted MW: 52.5 KDa).
Lane 2: Non-transfected lysate.
Western Blot detection against Immunogen (77.88 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant CBLC.
Immunogen
CBLC (AAH28915, 1 a.a. ~ 474 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MALAVAPWGRQWEEARALGRAVRMLQRLEEQCVDPRLSVSPPSLRDLLPRTAQLLREVAHSRRAAGGGGPGGPGGSGDFLLIYLANLEAKSRQVAALLPPRGRRSANDELFRAGSRLRRQLAKLAIIFSHMHAELHALFPGGKYCGHMYQLTKAPAHTFWRESCGARCVLPWAEFESLLGTCHPVEPGCTALALRTTIDLTCSGHVSIFEFDVFTRLFQPWPTLLKNWQLLAVNHPGYMAFLTYDEVQERLQACRDKPGSYIFRPSCTRLGQWAIGYVSSDGSILQTIPANKPLSQVLLEGQKDGFYLYPDGKTHNPDLTELGQAEPQQRIHVSEEQLQLYWAMDSTFELCKICAESNKDVKIEPCGHLLCSCCLAAWQHSDSQTCPFCRCEIKGWEAVSIYQFHGQATAEDPGNSSDQEGRELELGQVPLSAPPLPPRPDLPPRKPRNAQPKVRLLKGNSPPAALGPQDPAPA
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (74); Rat (75)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (77.88 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of CBLC expression in transfected 293T cell line by CBLC monoclonal antibody (M01), clone 3F10.
Lane 1: CBLC transfected lysate (Predicted MW: 52.5 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
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Gene Info — CBLC
Entrez GeneID
23624GeneBank Accession#
BC028915Protein Accession#
AAH28915Gene Name
CBLC
Gene Alias
CBL-3, CBL-SL, RNF57
Gene Description
Cas-Br-M (murine) ecotropic retroviral transforming sequence c
Omim ID
608453Gene Ontology
HyperlinkGene Summary
CBL proteins, such as CBLC, are phosphorylated upon activation of a variety of receptors that signal via protein tyrosine kinases. Through interactions with proteins containing SRC (MIM 190090) homology-2 (SH2) and SH3 domains, CBL proteins modulate downstream cell signaling (Keane et al., 1999 [PubMed 10362357]).[supplied by OMIM
Other Designations
Cas-Br-M (murine) ectropic retroviral transforming sequence c
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Interactome
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Pathway
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