CBLC purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human CBLC protein.
Immunogen
CBLC (AAH28915.1, 1 a.a. ~ 474 a.a) full-length human protein.
Sequence
MALAVAPWGRQWEEARALGRAVRMLQRLEEQCVDPRLSVSPPSLRDLLPRTAQLLREVAHSRRAAGGGGPGGPGGSGDFLLIYLANLEAKSRQVAALLPPRGRRSANDELFRAGSRLRRQLAKLAIIFSHMHAELHALFPGGKYCGHMYQLTKAPAHTFWRESCGARCVLPWAEFESLLGTCHPVEPGCTALALRTTIDLTCSGHVSIFEFDVFTRLFQPWPTLLKNWQLLAVNHPGYMAFLTYDEVQERLQACRDKPGSYIFRPSCTRLGQWAIGYVSSDGSILQTIPANKPLSQVLLEGQKDGFYLYPDGKTHNPDLTELGQAEPQQRIHVSEEQLQLYWAMDSTFELCKICAESNKDVKIEPCGHLLCSCCLAAWQHSDSQTCPFCRCEIKGWEAVSIYQFHGQATAEDPGNSSDQEGRELELGQVPLSAPPLPPRPDLPPRKPRNAQPKVRLLKGNSPPAALGPQDPAPA
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (74); Rat (75)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of CBLC expression in transfected 293T cell line (H00023624-T01) by CBLC MaxPab polyclonal antibody.
Lane 1: CBLC transfected lysate(52.50 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — CBLC
Entrez GeneID
23624GeneBank Accession#
BC028915Protein Accession#
AAH28915.1Gene Name
CBLC
Gene Alias
CBL-3, CBL-SL, RNF57
Gene Description
Cas-Br-M (murine) ecotropic retroviral transforming sequence c
Omim ID
608453Gene Ontology
HyperlinkGene Summary
CBL proteins, such as CBLC, are phosphorylated upon activation of a variety of receptors that signal via protein tyrosine kinases. Through interactions with proteins containing SRC (MIM 190090) homology-2 (SH2) and SH3 domains, CBL proteins modulate downstream cell signaling (Keane et al., 1999 [PubMed 10362357]).[supplied by OMIM
Other Designations
Cas-Br-M (murine) ectropic retroviral transforming sequence c
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Interactome
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Pathway
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