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ZNF278 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00023598-T01
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-ZNF278 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 59.18
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-ZNF278 antibody (H00023598-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00023598-T01
    PATZ1 transfected lysate.
    Western Blot
    QC Testing of H00023598-T01
    Lane 1: PATZ1 transfected lysate ( 59.18 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Gene Name:
  • PATZ1
  • Gene Alias:
  • MAZR,PATZ,RIAZ,ZBTB19,ZNF278,ZSG,dJ400N23
  • Gene Description:
  • POZ (BTB) and AT hook containing zinc finger 1
  • Gene Summary:
  • The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1;22)(p36.1;q12). The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene. [provided by RefSeq
  • Other Designations:
  • BTB-POZ domain zinc finger transcription factor,MAZ-related factor,POZ-AT hook-zinc finger protein,zinc finger protein 278
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