ORC3L monoclonal antibody (M01), clone 3D3
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant ORC3L.
Immunogen
ORC3L (AAH35494, 602 a.a. ~ 711 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
ALNNPYYYLKNEALKSEEGCIPNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAAEKMDANSATSEEMNEIIHARFIRAVSELELLGFIKPTKQKTDHVARLTWGGC
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (79); Rat (82)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ORC3L is approximately 0.03ng/ml as a capture antibody.ELISA
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Gene Info — ORC3L
Entrez GeneID
23595GeneBank Accession#
BC035494Protein Accession#
AAH35494Gene Name
ORC3L
Gene Alias
LAT, LATHEO, ORC3
Gene Description
origin recognition complex, subunit 3-like (yeast)
Omim ID
604972Gene Ontology
HyperlinkGene Summary
The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Studies of a similar gene in Drosophila suggested a possible role of this protein in neuronal proliferation and olfactory memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000016835|OTTHUMP00000040611|homolog of latheo, Drosophila|origin recognition complex, subunit 3
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Interactome
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