ORC6L (Human) IP-WB Antibody Pair
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (74); Rat (70)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of ORC6L transfected lysate using rabbit polyclonal anti-ORC6L and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-ORC6L.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-ORC6L (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-ORC6L (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — ORC6L
Entrez GeneID
23594Gene Name
ORC6L
Gene Alias
ORC6
Gene Description
origin recognition complex, subunit 6 like (yeast)
Omim ID
607213Gene Ontology
HyperlinkGene Summary
The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. It has been shown that this protein and and ORC1L are loosely associated with the core complex consisting of ORC2L, -3L, -4L and -5L. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis. [provided by RefSeq
Other Designations
origin recognition complex subunit 6|origin recognition complex, subunit 6 homolog-like
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Interactome
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Pathway
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