ORC6L monoclonal antibody (M04), clone 3C4

Catalog # H00023594-M04

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Size:100 ug
Price: USD $ 335.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Western Blot (Transfected lysate)
Application

Western Blot (Transfected lysate)

Western Blot analysis of ORC6L expression in transfected 293T cell line by ORC6L monoclonal antibody (M04), clone 3C4.

Lane 1: ORC6L transfected lysate(28.1 KDa).
Lane 2: Non-transfected lysate.

Immunoprecipitation
Application

Immunoprecipitation

Immunoprecipitation of ORC6L transfected lysate using anti-ORC6L monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with ORC6L MaxPab rabbit polyclonal antibody.

Immunofluorescence
Application

Immunofluorescence

Immunofluorescence of monoclonal antibody to ORC6L on HeLa cell . [antibody concentration 10 ug/ml]

QC Test

Western Blot detection against Immunogen (53.46 KDa) .

  • Specification

    Product Description

    Mouse monoclonal antibody raised against a full-length recombinant ORC6L.

    Immunogen

    ORC6L (AAH63565, 1 a.a. ~ 252 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    Sequence

    MGSELIGRLAPRLGLAEPDMLRKAEEYLRLSRVKCVGLSARTTETSSAVMCLDLAASWMKCPLDRAYLIKLSGLNKETYQSCLKSFECLLGLNSNIGIRDLAVQFSCIEAVNMASKILKSYESSLPQTQQVDLDLSRPLFTSAALLSACKILKLKVDKNKMVATSGVKKAIFDRLCKQLEKIGQQVDREPGDVATPPRKRKKIVVEAPAKEMEKVEEMPHKPQKDEDLTQDYEEWKRKILENAASAQKATAE

    Host

    Mouse

    Reactivity

    Human

    Interspecies Antigen Sequence

    Mouse (74); Rat (70)

    Isotype

    IgG3 Kappa

    Quality Control Testing

    Antibody Reactive Against Recombinant Protein.

    Western Blot detection against Immunogen (53.46 KDa) .

    Storage Buffer

    In 1x PBS, pH 7.4

    Storage Instruction

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

  • Applications

    Western Blot (Transfected lysate)

    Western Blot analysis of ORC6L expression in transfected 293T cell line by ORC6L monoclonal antibody (M04), clone 3C4.

    Lane 1: ORC6L transfected lysate(28.1 KDa).
    Lane 2: Non-transfected lysate.

    Western Blot (Recombinant protein)

    Immunoprecipitation

    Immunoprecipitation of ORC6L transfected lysate using anti-ORC6L monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with ORC6L MaxPab rabbit polyclonal antibody.

    ELISA

    Immunofluorescence

    Immunofluorescence of monoclonal antibody to ORC6L on HeLa cell . [antibody concentration 10 ug/ml]
  • Gene Info — ORC6L

    Entrez GeneID

    23594

    GeneBank Accession#

    BC063565

    Protein Accession#

    AAH63565

    Gene Name

    ORC6L

    Gene Alias

    ORC6

    Gene Description

    origin recognition complex, subunit 6 like (yeast)

    Omim ID

    607213

    Gene Ontology

    Hyperlink

    Gene Summary

    The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. It has been shown that this protein and and ORC1L are loosely associated with the core complex consisting of ORC2L, -3L, -4L and -5L. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis. [provided by RefSeq

    Other Designations

    origin recognition complex subunit 6|origin recognition complex, subunit 6 homolog-like

  • Interactome
  • Pathway
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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