ORC6L MaxPab rabbit polyclonal antibody (D02)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human ORC6L protein.
Immunogen
ORC6L (AAH63565.1, 1 a.a. ~ 252 a.a) full-length human protein.
Sequence
MGSELIGRLAPRLGLAEPDMLRKAEEYLRLSRVKCVGLSARTTETSSAVMCLDLAASWMKCPLDRAYLIKLSGLNKETYQSCLKSFECLLGLNSNIGIRDLAVQFSCIEAVNMASKILKSYESSLPQTQQVDLDLSRPLFTSAALLSACKILKLKVDKNKMVATSGVKKAIFDRLCKQLEKIGQQVDREPGDVATPPRKRKKIVVEAPAKEMEKVEEMPHKPQKDEDLTQDYEEWKRKILENAASAQKATAE
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (74); Rat (70)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of ORC6L expression in transfected 293T cell line (H00023594-T01) by ORC6L MaxPab polyclonal antibody.
Lane 1: ORC6L transfected lysate(27.83 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of ORC6L transfected lysate using anti-ORC6L MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with ORC6L purified MaxPab mouse polyclonal antibody (B01P) (H00023594-B01P).Immunofluorescence
Immunofluorescence of purified MaxPab antibody to ORC6L on HeLa cell. [antibody concentration 20 ug/ml] -
Gene Info — ORC6L
Entrez GeneID
23594GeneBank Accession#
BC063565.1Protein Accession#
AAH63565.1Gene Name
ORC6L
Gene Alias
ORC6
Gene Description
origin recognition complex, subunit 6 like (yeast)
Omim ID
607213Gene Ontology
HyperlinkGene Summary
The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. It has been shown that this protein and and ORC1L are loosely associated with the core complex consisting of ORC2L, -3L, -4L and -5L. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis. [provided by RefSeq
Other Designations
origin recognition complex subunit 6|origin recognition complex, subunit 6 homolog-like
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Interactome
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Pathway
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